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Research Institute

Research & Development

Advancing Eye Care Through Research

At Prism Eye Institute, research is integrated into our daily patient care. Through clinical trials, peer-reviewed publications, and academic collaboration, we continuously work to improve outcomes across retina, glaucoma, cataract, cornea, and neuro-ophthalmology.

Improving standard of care thru research

– Access to emerging therapies
– High clinical volume enabling meaningful data
– Collaboration between surgeons and referring optometrists
– Academic & industry partnerships
– Commitment to evidence-based medicine

Meet Our Research Team

Prism Research Institute

Dr. Ike Ahmed

Chief Innovation Officer

Walid Abdelghaffar, MD, MSc, PhD, FRCS, FRCSC
Dr. Walid Abdelghaffar

Sub Investigator

Dr. Irfan Kherani

Sub Investigator

Joshua C. Teichman, MD
Dr. Joshua Teichman

Sub Investigator

Dr. Matt Schlenker

Sub Investigator

Suneet Khurana

Research Manager

David Chen MD

Research Fellow

Maria Orejarena MD

Research Associate

Edward Tran MD

Research Associate

Gabriel Ayub MD

Research Associate

Fareesa Begum

Research Associate


Active Studies


Icare Xen; Watering Drinking Test

Primary Objective
· To detect peak intraocular pressure (IOP) using Water Drinking Test (WDT) and iCare home tonometry, before and after IMS or Xen implantation, to assess efficacy of these procedures.

YESBIO Biocon

Primary Objective
· To describe the patient journey leading to the first intravitreal injection of biosimilar aflibercept (YESAFILI™) in Canadian patients with DME, nAMD, or RVO, including:
o Physician decision-making
o Patient characteristics
o Prior treatment history
o Rationale for selecting a biosimilar over the reference biologic

MF IOLX Puresee study

Primary Objective
· To evaluate patient-reported satisfaction and quality of vision following exchange of a non-tolerated multifocal intraocular lens (MFIOL) to a purely refractive extended depth of focus (EDOF) IOL (TECNIS PureSee™ or PureSee™ Toric), including resolution of dysphotopsias and other visual complaints.

Corvis Study

Primary Objective
· To assess whether baseline corneal biomechanical measurements; corneal hysteresis (CH) and stiffness parameter at first applanation (SP-A1)—predict complete and qualified surgical success up to 1 year following bleb-forming glaucoma surgery

AURN001-NA-LTS study

Primary Objective
· To evaluate the long-term safety of AURN001 and its drug substance constituents (neltependocel and/or Y-27632) in participants with corneal edema secondary to corneal endothelial dysfunction who were previously treated in an AURN001 study.

MIST Study

Primary Objective
· To evaluate the safety, feasibility, and intraocular pressure (IOP)–lowering effect of the MIST device performed ab externo at the slit lamp in patients with primary open-angle glaucoma (POAG).

XEN Multicenter study

Primary Objective
· To compare efficacy and safety outcomes between a surgeon’s first 10 XEN implant cases and subsequent cases (≥11) in order to characterize the learning curve for the ab-interno gelatin stent with Mitomycin C (MMC).

CTA: Do I qualify?

XEN ECC – Endothelial cell density

Primary Objective
· To determine the impact of Xen-45 gelatin stent implantation with mitomycin C (MMC) on post-operative corneal endothelial cell density (ECD) compared with trabeculectomy and tube shunt procedures, as standalone or combined with phacoemulsification.

IOL Calcification

Primary Objective
· To evaluate and compare best-corrected distance and near visual acuity (BCVA) before and after surgical exchange of a calcified intraocular lens (IOLo

iTrack Registry

Primary Objective
· To prospectively collect standardized real-world safety and effectiveness data for glaucoma surgeries involving the iTrack™ or iTrack™ Advance devices, including canaloplasty, GATT, combined MIGS procedures, and procedures combined with micro drug-delivery devices

GLK-411-01 Preserflo Microshunt in POAG

Primary Objective
· To evaluate the safety and effectiveness of the PRESERFLO MicroShunt in adults with primary open-angle glaucoma (POAG) who have failed prior medical and surgical therapy

PanOptix Pro study

Primary Objective
· To evaluate binocular best-corrected distance visual acuity (BCDVA) at 3 months following bilateral PanOptix Pro implantation.

Do I qualify?

Fill out the submission form below to check if you could be eligible to participate for a study.

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Our Locations

Brampton

Brampton
7700 Hurontario Street, Unit 605
Brampton, Ontario  L6Y 4M3

905.456.3937
Mon. - Fri. 8:00AM – 5:00PM

Mississauga-Oakville

Mississauga-Oakville
2201 Bristol Circle, Suite 100,
Oakville, Ontario L6H 0J8

905.456.3937
Mon. - Fri. 8:00AM – 5:00PM
Sat.
8:00AM – 4:00PM